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Rabbit Anti-ATP1B2  antibody (bs-1152R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-1152R
英文名稱 Rabbit Anti-ATP1B2  antibody
中文名稱 鈉鉀ATP酶通道蛋白抗體
別    名 AT1B2_HUMAN; Adhesion molecule in glia (AMOG); Sodium/potassium-dependent ATPase subunit beta-2; ATPase Na+/K+ transporting subunit beta 2;  
Specific References  (4)     |     bs-1152R has been referenced in 4 publications.
[IF=41.444] Sun, Zeguo. et al. LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer. MOL CANCER. 2022 Dec;21(1):1-24  WB ;  Human.  
[IF=6.304] Shiman Zuo. et al. Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy. Cell Death Dis. 2021 Feb;12(2):1-15  WB ;  Human.  
[IF=4.088] Yanhui Jia. et al. The deacetylation of Akt by SIRT1 inhibits inflammation in macrophages and protects against sepsis. EXP BIOL MED. ;():  WB ;  Human,Mouse.  
[IF=1.689] Wang HY et al. Occludin Endocytosis is Involved in Disruption of the Intestinal Epithelial Barrier in a Mouse Model of Alcoholic Steatohepatitis. J Dig Dis. 2019 Jul 12.  WB ;  Human.  
研究領域 通道蛋白  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATP1b2: 201-290/290 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq, Jul 2008]

Function:
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.

Subunit:
Composed of three subunits: alpha (catalytic), beta and gamma.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the X(+)/potassium ATPases subunit beta family.

SWISS:
P14415

Gene ID:
482

Database links:

Entrez Gene: 482 Human

Omim: 182331 Human

SwissProt: P14415 Human

Unigene: 643540 Human



通道蛋白(Channel Protein)
鈉鉀ATP酶是位于細胞膜上的一種糖蛋白,與ATP 的分解和細胞內外鈉、鉀離子的轉運密切相關,哺乳動物各種組織細胞的鈉鉀ATP 酶的免疫學特性基本相同。
產品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti- ATPase Na+/ K+ beta 2 (bs-1152R) at 1/200 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kDa Observed band size: 50 kDa
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